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The Lead

Dengue fever outbreak infects thousands in war-torn Yemen

June 18, 2015 | by AHMED AL-HAJ, Associated Press | Comments

Mountains of uncollected garbage, sewage and heat have contributed to the spread of the disease.

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New antibody specificity portal bolsters biomedical research reliability

July 23, 2015 1:26 pm | by Van Andel Research Institute | Comments

For years, a crisis has been brewing in molecular biology. The problem is that antibodies--research tools used to identify key proteins at work in a cell--aren't always what they seem. Unreliable antibodies have led to numerous instances of false findings....

Investigators developed a tool for more accurate interpretation of biomedical research

July 23, 2015 1:15 pm | by VIB (the Flanders Institute for Biotechnology) | Comments

Investigators affiliated with VIB and UGent recently achieved great success with a study involving biomedical research on mouse models. The research group of Prof Peter Vandenabeele (VIB/UGent) recently used tangible examples....

Basic research needed to speed cures for some diseases

July 23, 2015 1:01 pm | by Jonathon Shacat, FDA | Comments

The FDA is calling for increased focus on the underlying biology of diseases like Alzheimer’s and diabetes, noting that the discovery of biomarkers has led to important breakthroughs for cancer and HIV/AIDS.

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FDA to study impact of efficacy information in DTC ads

July 23, 2015 12:59 pm | by Kellen Owings, FDA | Comments

In its latest study of direct-to-consumer ads, the FDA wants to know if the inclusion of efficacy information in drug advertisements affects how patients perceive the drug. For the two-part study announced Monday ...

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Web app helps researchers explore cancer genetics

July 23, 2015 11:46 am | by Brown University | Comments

Brown University computer scientists have developed a new interactive tool to help researchers and clinicians explore the genetic underpinnings of cancer. The tool -- dubbed MAGI, for Mutation Annotation and Genome Interpretation ...

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TSRI researcher wins $4.5 million in grants to support development of AIDS vaccine

July 23, 2015 11:42 am | by Scripps Research Institute | Comments

The Scripps Research Institute (TSRI) has been awarded two grants from the Bill & Melinda Gates Foundation totaling more than $4.5 million to fund efforts to develop a vaccine against HIV/AIDS. "We are delighted by the Gates Foundation's support of this critical work"....

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New 'chemotherapy booster' could treat lung and pancreatic cancer

July 23, 2015 11:40 am | by Institute of Cancer Research | Comments

A new drug that blocks cancer's escape route from chemotherapy could be used to treat deadly lung and pancreatic cancers, new research reports. Scientists have shown in human cancer cells and in mice that the drug ...

Zebrafish reveal drugs that may improve bone marrow transplants

July 23, 2015 11:26 am | by PRNewswire | Comments

Using large-scale zebrafish drug-screening models, researchers at Boston Children's Hospital have identified a potent group of chemicals that helps bone marrow transplants engraft or "take." The findings, published in the July 23 issue of Nature ...

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The Phase 3 development strategy for a novel glaucoma treatment

July 23, 2015 11:20 am | by BUSINESS WIRE | Comments

Inotek Pharmaceuticals Corporation, a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of therapies for ocular diseases, today announced the Phase 3 development strategy of its lead glaucoma drug, trabodenoson....

FDA grants "Fast Track" to Omeros' Complement Inhibitor OMS721 for aHUS

July 23, 2015 11:13 am | by PRNewswire | Comments

Omeros Corporation announced that the U.S. Food and Drug Administration (FDA) granted Fast Track designation to OMS721 for the treatment of patients with atypical hemolytic uremic syndrome (aHUS). OMS721 is the company's lead human monoclonal antibody....

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Surging new drug sales highlight strong Bristol-Myers Q2

July 23, 2015 10:54 am | by LINDA A. JOHNSON, AP Business Writer | Comments

Surging sales for new cancer, heart and hepatitis C medicines helped drugmaker Bristol-Myers Squibb Co. beat Wall Street expectations, and it boosted its 2015 profit forecast. Still, a sizeable acquisition charge triggered a steep tax bill....

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'BORG' peptides improve biocompatibilty of polysulfone for use in dialysis

July 23, 2015 10:51 am | Comments

Arch Biopartners Inc (Arch) or (the Company) announced that Arch scientists have published details of their new technology and its potential applications in the area of dialysis. Arch scientists Daniel Muruve, Randall Irvin and Elisabeth Davis ...

First patient enrolls in clinical trial for treatment of cluster headaches

July 23, 2015 10:41 am | by GLOBE NEWSWIRE | Comments

Capnia, Inc., focused on the development and commercialization of novel products based on its proprietary technologies for precision metering of gas flow, announced enrollment of the first patient in an investigator-sponsored clinical trial....

Study: E-cigarettes just as addictive as traditional smokes

July 23, 2015 10:01 am | by Andy Szal, Digital Reporter | Comments

A recent study indicated that electronic cigarettes could be just as addictive as their conventional predecessors. The report in the journal Chemical Research in Toxicology analyzed commercial samples of liquids produced for e-cigarettes.

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Capsugel expanding pharmaceutical product development at its Edinburgh facility

July 23, 2015 9:54 am | Comments

Capsugel, a global leader in delivering high-quality, innovative dosage forms and solutions, today announced a major expansion of its facility in Edinburgh, Scotland, to meet rising customer demand for its specialized pharmaceutical product development....

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