Bench to Bassinet Program Seeks Congenital Heart Disease Treatments
The Bench to Bassinet Program consists of three major research efforts. The two newest, highlighted in the journal article, are the Pediatric Cardiac Genomic Consortium and the Cardiovascular Development Consortium. The New England Research Institutes serves as the coordinating center for the overall program.
Investigators in the Pediatric Cardiac Genomics Program will search the human genome for genetic defects that lead to heart problems. The participating research centers will study genetic data from hundreds of individuals born with congenital heart disease to uncover genes that may cause congenital heart disease, and how those genes influence the outcome of therapy. The institutes conducting this research are: The Children's Hospital Boston and the Brigham and Women's Hospital, Mass.; The Children's Hospital of Philadelphia, Pa. ; Columbia University Health Science, New York City; the Mount Sinai School of Medicine, New York City; and Yale University, New Haven, Conn.
Researchers still have many questions about the various complex pathways that lead to the creation of a healthy heart. Advances in technology and recent research findings make this an opportune time to launch an intensive collaboration designed to provide a comprehensive picture of the key steps in the development of healthy and abnormal hearts. Teams in the Cardiovascular Development Consortium will use state-of-the-art techniques to offer vital insights into heart development. The research institutes are: the J. David Gladstone Institutes, San Francisco, Calif.; Harvard University Medical School, Boston, Mass; the University of Pittsburgh, Pa.; and the University of Utah, Salt Lake City.These two new programs align with the NHLBI-funded Pediatric Heart Network (http://www.pediatricheartnetwork.com/), a group of academic institutions in the United States and Canada conducting research to determine optimal therapies for children with congenital and acquired heart disease. Together, these three research efforts provide the framework to move fundamental knowledge rapidly into clinical practice, and to use insights from clinical practice to inform basic and genetic research. Who:
Gail Pearson, M.D., Sc.D., chief of the Heart Development and Structural Diseases Branch, and director of the Adult and Pediatric Cardiac Research Program in the NHLBI's Division of Cardiovascular Sciences, is available to comment on the significance and goals of the project.Contact:
To schedule interviews, contact the NHLBI Communications Office at 301-496-4236 or firstname.lastname@example.org.
The National Heart, Lung, and Blood Institute (NHLBI) plans, conducts, and supports research related to the causes, prevention, diagnosis, and treatment of heart, blood vessel, lung, and blood diseases; and sleep disorders. The Institute also administers national health education campaigns on women and heart disease, healthy weight for children, and other topics. NHLBI press releases and other materials are available online at: www.nhlbi.nih.gov.