Introducing ProVance™ pre-packed Protein A columns, a high-performance disposable chromatography solution to help meet the growing demand for downstream purification. Increasingly, major biopharmaceutical companies are shifting to single-use manufacturing for greater portability, scalability and the rapid deployment of biologics. ProVance™ columns combine proprietary incompressible silica with cost-effective Protein A and disposable column hardware. The high capacity columns can reduce operating costs by 40-60 percent and are ideally suited for single-batch or single-campaign use eliminating the need for significant cleaning validations and long-term storage. The columns are available in a range of sizes for early screening and up to full-scale GMP manufacturing. Columns for use in GMP manufacturing come complete with documentation for regulatory support, shipping studies, and leachables, and extractables.