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Science, Patients Driving Rare Disease Drug Research Surge

March 25, 2015 2:24 pm | by LINDA A. JOHNSON, AP Business Writer | News | Comments

The global pharmaceutical industry is pouring billions of dollars into developing treatments for rare diseases, which once drew little interest from major drugmakers but now point the way toward a new era of innovative therapies and big profits.

American Who Contracted Ebola Now in Critical Condition

March 17, 2015 8:21 am | by BRETT ZONGKER, Associated Press | News | Comments

An American health care worker who contracted Ebola while volunteering in a Sierra Leone...

American Who Contracted Ebola Arrives at Maryland Hospital

March 13, 2015 8:22 am | News | Comments

An American healthcare worker who contracted Ebola while volunteering in a Sierra Leone...

RetroVirox Awarded $3M NIH Grant to Develop Drugs to Cure HIV Infection

March 12, 2015 8:16 am | News | Comments

RetroVirox, Inc. a biotechnology company focused on viral diseases, announced today it has...

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Persevering Past Roadblocks to Build a Promising Ebola Vaccine

February 10, 2015 8:27 am | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

It took 16 years of twists and turns. Over and over, Dr. Nancy Sullivan thought she was close to an Ebola vaccine, only to see the next experiment fail. But it is those failures that Sullivan credits for finally leading her to a vaccine promising enough to test in parts of West Africa ravaged by Ebola.

Inherited Gene Variation Helps Explain Drug Toxicity in Patients Of East Asian Ancestry

January 27, 2015 7:01 am | News | Comments

About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer.

Dr. Fauci: It's a "Shame" Children Are Not Being Vaccinated for Measles

January 26, 2015 9:03 am | Videos | Comments

The measles outbreak with roots in Disneyland continues to spread, with at least 75 confirmed cases in six states. At least 54 of those cases have been traced back to the resort, and many of those infected were not vaccinated. National Institute of Allergy and Infectious Diseases director Dr. Anthony Fauci joins "CBS This Morning" to discuss the severity of the outbreak.


US: Long-Awaited Ebola Vaccine Study Coming Soon in Liberia

January 22, 2015 4:32 pm | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

The first study will compare the two experimental vaccines with dummy shots in hopes of proving whether either really protects against the Ebola virus, which has devastated Liberia, Guinea and Sierra Leone over the past year. A second study of one of the vaccines is being planned for Sierra Leone.

Senator Warren to File Bill Targeting Top Pharma Companies

January 22, 2015 2:24 pm | by STEVE LeBLANC, Associated Press | News | Comments

Warren's bill would require that whenever drug companies enter into a settlement with the government over alleged wrongdoing, they must pay a portion of their annual profits over five years to support research at the NIH and the FDA.   

AMRI Receives NIH Contract Award

January 19, 2015 9:29 am | News | Comments

AMRI has received a 10-year federal contract award from the NIH for drug development and manufacturing services. This NIH/National Institute of Neurological Disorders and Stroke award will support NIH's Drug Manufacturing and Formulation Program, which is a component of the Blueprint Neurotherapeutics Network. AMRI has supported the NIH BPN since 2011, providing chemistry services and discovery technologies.

Study: Little Evidence Opioids Help Chronic Pain

January 15, 2015 8:55 am | Videos | Comments

More than 100 million Americans suffer from chronic pain, with five to eight million needing powerful narcotics to fight the pain. However, an expert panel is declaring there is little evidence these treatment programs work     

Pill Terminator Seeks to Improve in-Home Drug Disposal

January 12, 2015 4:10 pm | by Andrew Szal, Editor, Pharmaceutical Processing | News | Comments

The National Institutes of Health says the U.S. alone consumes three-quarters of the world’s prescriptions drugs despite accounting for just 5 percent of its population, and when symptoms subside, treatment directives change or medications expire, options for disposing of the remaining doses can be limited.


Fake Bar Part of Research into Anti-Drinking Drug

January 2, 2015 8:08 am | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

There's no skunky bar odor amid the beer taps. Instead of booze, colored water fills the bottles. The real alcohol is locked away but still close enough for the extra temptation of smell — and to test the safety of a new drug designed to help heavy drinkers say "when" sooner than usual.

Survey: E-Cigs Surpass Regular Cigarettes in Teen Use

December 16, 2014 8:34 am | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

Even as tobacco smoking by teens dropped to new lows, use of e-cigarettes reached levels that surprised researchers. The findings marked the survey's first attempt to measure the use of e-cigarettes by people that young.     

Obama: Ebola Still A Priority

December 3, 2014 8:18 am | by JIM KUHNHENN, Associated Press; STACY A. ANDERSON, Associated Press | News | Comments

Declaring the "fight is nowhere close to being over," President Barack Obama heralded strides in the effort to confront Ebola in West Africa and in protecting the U.S. against the spread of the deadly virus. He said squelching the disease remains an urgent priority even if the American public's attention has shifted elsewhere.

Ebola Vaccine Seems Safe in First-Stage Testing

November 26, 2014 6:10 pm | by By Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

An experimental Ebola vaccine appears safe and triggered signs of immune protection in the first 20 volunteers to test it, U.S. researchers have reported. The vaccine is designed to spur the immune system's production of anti-Ebola antibodies. 

Government Wants More Clinical Trial Results Made Public

November 19, 2014 3:28 pm | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

Doctors and patients may soon find it easier to learn if clinical trials of treatments worked or not, as the government proposed new rules Wednesday expanding what researchers are required to publicly report.       


Ebola Drug Testing Sparks Ethics Debate

November 12, 2014 2:22 pm | by MATTHEW PERRONE, AP Health Writer | News | Comments

Health officials are scrambling to begin human testing of a handful of experimental drugs for Ebola. But the effort has sparked an ethical debate over how to study unproven medicines amid an outbreak that has killed nearly 5,000.    

Feds vs. States: Who Decides on Ebola Quarantines

October 28, 2014 8:41 am | by JOSH LEDERMAN, Associated Press | News | Comments

For Americans wondering why President Barack Obama hasn't forced all states to follow a single, national rule for isolating potential Ebola patients, the White House has a quick retort: Talk to the Founding Fathers.      

Swissmedic Approves Trial for Ebola Vaccine

October 28, 2014 7:35 am | by The Associated Press | News | Comments

The Swiss agency that regulates new drugs has approved an application for a clinical trial with an experimental Ebola vaccine at the Lausanne University Hospital. Swissmedic said the trial will be conducted among 120 volunteer participants with support from the U.N. World Health Organization.

WHO: Millions of Ebola Vaccine Doses Ready in 2015

October 24, 2014 11:38 am | by Maria Cheng - AP Medical Writer - Associated Press | News | Comments

The World Health Organization says millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines will start being tested in March. Still, the agency warned it's not clear whether any of these will work against the deadly virus that has...

Nurses Infected With Ebola Being Treated With Experimental Drugs

October 17, 2014 8:26 am | Videos | Comments

Both Dallas nurses infected while treating an Ebola patient have been flown to better equipped facilities.                        

Why Nation's Top Doctors Say Ebola Won't Spread in US

October 7, 2014 8:37 am | by CONNIE CASS, Associated Press | News | Comments

Ebola has arrived in the United States and people are frightened. The nation's top infectious diseases expert says it's perfectly normal to feel anxious about a virus that kills so fast and is ravaging parts of West Africa.     

Experts Starting to Admit it May Take Vaccine to Stop Ebola in West Africa

October 6, 2014 8:31 am | by Helen Branswell, The Canadian Press | News | Comments

As West Africa's Ebola outbreak continues to rage, some experts are coming to the conclusion that it may take large amounts of vaccines and maybe even drugs — all still experimental and in short supply — to bring the outbreak under control.  

US Doctor Exposed to Ebola Virus Admitted to NIH

September 29, 2014 10:23 am | News | Comments

An American doctor who was exposed to the Ebola virus while volunteering in Sierra Leone was admitted Sunday to a hospital at the National Institutes of Health near the nation's capital.           

Navidea Awarded $1.67M Fast Track NIH SBIR Grant for Evaluation of Lymphoseek® in Cervical Cancer

September 23, 2014 9:12 am | News | Comments

Navidea Biopharmaceuticals today announced the receipt of an initial notice of award for a Fast Track Small Business Innovation Research (SBIR) grant providing for up to $1.67 million from the National Cancer Institute (NCI), National Institutes of Health (NIH), to fund evaluation of Lymphoseek ® (technetium Tc 99m tilmanocept) Injection in women with cervical cancer.

Soligenix Awarded $24.7M NIAID Contract to Develop Heat Stable RiVax Vaccine

September 19, 2014 8:11 am | News | Comments

The objectives of the contract are to advance the development of Soligenix's thermostabilization technology, ThermoVax, combined with the company's ricin toxin vaccine, Rivax, as a medical countermeasure (MCM) to prevent the effects of ricin exposure.

NIH: Ebola Unlikely to Become Airborne

September 18, 2014 8:55 am | by LAURAN NEERGAARD, AP Medical Writer | News | Comments

It's incredibly unlikely that Ebola would mutate to spread through the air, and the best way to make sure it doesn't is to stop the epidemic, a top government scientist told concerned lawmakers Wednesday.        

First UK Volunteer Gets Experimental Ebola Vaccine

September 17, 2014 12:51 pm | by The Associated Press | News | Comments

British scientists say a former nurse has become the first person in the country to receive an experimental Ebola vaccine in an early trial to test its safety. Ruth Atkins, 48, got the injection on Wednesday in Oxford, the first of 60 healthy volunteers in the U.K. who will receive the vaccine.

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