A one-stop-shop fluid management component supplier assures quality, streamlines processes, and limits costs. To be certain you receive the preeminent and safest single-use component, take time to evaluate your fluid-management supplier or a supplier under consideration by asking the 6 important questions we pose in this whitepaper.
Information about the health of a control system, the I/O systems, field devices and final control elements can be critical for plant operation and uptime. Timely diagnostic information can mean the difference between a quick repair and hours or days of unplanned downtime.
Approximately 25% of drugs in development worldwide are classified as highly potent, with this percentage expected to grow over the coming years. While such highly potent compounds can have significant benefits in the treatment of certain medical conditions, they present substantial challenges to the pharmaceutical industry.
For drying processes conducted under vacuum, precise control over process conditions is often critical. Accurately controlling the vacuum can help to significantly decrease total process time and improve process yields.
Of the wide range of vacuum pump technologies used in the pharmaceutical and chemical process industries, many incorporate wetted materials that prove problematic because of poor corrosion resistance.
Over the past 25 years considerable efforts have been made to develop a low cost, environmentally friendly, moisture specific method of material analysis. Leading these endeavors is Arizona Instrument LLC, who has successfully designed the Computrac® Vapor Pro® series of moisture analyzers.
The Computrac® Vapor Pro® Rx is an excellent alternative to Karl Fischer titration offering equivalent results, easier usage, and faster test times than the Karl Fischer when testing lyophilization closures. The instrument is highly durable, and since it uses no solvents or reagents, it is a greener alternative to Karl Fischer analysis.
This white paper reviews the OSHA National Emphasis Program for combustible dust, the NFPA standards that address explosion hazards, how to identify these hazards, and equipment used for explosion protection. It will also examine the most common shortfalls to compliance and how to avoid them.
A clinical trials facility was at risk of losing temperature data to monitoring equipment failure. They installed a monitoring system that identified an equipment failure, saving hundreds of thousands worth of research. “[The monitoring system] saved the costs of the study’s products ... These studies enhance lives, so the samples and products involved in the trials need to be safeguarded, accurately and reliably.”
When a powder processing operation involves multiple components, providing protection against static spark ignition of flammable or explosive atmospheres can be daunting. A recently updated “Applications Spotlight” section of the Newson Gale website provides detailed information explaining how various types of processing equipment can be reliably protected by an integrated system based on their Earth-Rite® Multipoint controller. Read more here
When a processing operation involves multiple components, providing protection against static spark ignition of flammable or explosive ambients can be daunting. A recently updated “Applications Spotlight” section of the Newson Gale website provides detailed information how various types of processing equipment can be reliably protected by an integrated system based on their Earth-Rite® Multipoint controller.
Download this combined PDF of 10 Must-read Articles: “Quality, Metrology, and cGMP/FDA Regulations: 10 articles on how to reduce the risks of failed inspections, poor quality management systems, and bad measurement practices” Let our subject matter experts show you how to attain and maintain GxP-compliant environmental monitoring and validation applications. Get PDF
Supply chain planning involves functions such as demand forecasting and planning, distribution inventory planning, and plant capacity planning and scheduling. The right mix of strategy, education, and systems can have a very high impact on a pharmaceutical manufacturer’s overall operations—and ultimately its bottom line.
Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate) is a common nonionic surfactant, emulsifier and solubilizer that is used in a wide variety of industries and applications. A well-developed analytical method is crucial for accurately quantitating polysorbates. Due to the chemical structure and chemical properties of polysorbate 80, it cannot be accurately quantitated by analytical methods such gas chromatography or liquid chromatography with ultraviolet absorption. This whitepaper discusses how a new analytical method using High Performance Liquid Chromatography (HPLC) with Charged Aerosol Detection (CAD) accurately quantitates polysorbate 80 in a pharmaceutical formulation.
This new infographic created by Vaisala’s validation engineers describes 10 Points of a GAMP-based validation that ensure an environmental monitoring system will function as expected. It refers to the 3 most common types of continuous monitoring systems, and outlines the validation steps and extent of validation effort for each.
Bulk ingredients for pharmaceutical products are shipped and handled almost exclusively on wood pallets. When the ingredients are needed for use in production, however, the wood pallets have to be removed. This means drug manufacturers must find a way to safely transfer bulk ingredients—whether in cartons, super sacks, bulk boxes, drums tubs or bags—onto a captive, production-dedicated plastic pallet used only within the processing area. The safest transfer solution maintains the load’s integrity, prevents potential contamination from the transport pallet and protects workers from possible injury, all while operating at a speed that does not inhibit production rates.