Anti-CD22 scFv h(41BB-CD3ζ) CART, pCDCAR1

The vector of anti-CD22 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD22. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD22 antibody linked to CD137 (4-1BB) and CD3-zeta signaling domains. And the vector product was designed for the treatment of acute lymphoblastic leukemia (ALL) .http://www.creative-biolabs.com/car-t/pcdcar1-cd22-h-bbζ-t-105.htm
 

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